Product Details
-Quick information-
Product Name: Abiraterone Acetate Powder CAS 154229-18-2
Synonyms: 17-(3-pyridyl)-5,16-androstadien-3beta-acetate;(3)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate (Ester); CB 7630; 3β-acetoxy-17-(3-pyridyl)androsta-5,16-diene; (3beta)-17-(3-pyridinyl)-Androsta-5,16-dien-3-ol acetate (ester); 2-((3S,8R,9S,10R,13S,14S)-10,13-diMethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)acetate
MF: C26H33NO2
MW: 391.55
Molar mass: 349.509 g/mol
Appearance: white or off-white powder
CAS: 154229-18-2
-Description-
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What is Abiraterone Acetate Powder?
Abiraterone Acetate Powder CAS 154229-18-2 is a white to white, non-hygroscopic, crystalline powder. Its molecular formula is C26H33NO2and it has a molecular weight of 391.55.
It is known as chemical name 17-(3-pyridyl)-5,16-androstadien-3beta-acetate and brand name zytiga, is the precursor drug of abitrone and the drug targeting the androgen receptor signal pathway. Abitrone is a highly selective and powerful inhibitor of cytochrome oxidase CYP17. Its inhibition is irreversible and 10-30 times stronger than ketoconazole. It is is used in combination with prednisone for the treatment of castrated patients with refractory prostate cancer who have previously received docetaxel containing chemotherapy.
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-Usage-
Abiraterone acetate is mainly used in combination with prednisone for the treatment of patients after receiving chemotherapy containing docetaxel
1. Metastatic castration resistant prostate cancer (CRPC)
2. Castration sensitive prostate cancer patients (CSPC) with high risk of metastasis.
-Specifications-
Abiraterone Acetate Powder CAS 154229-18-2 |
Items |
Specifications |
Results |
Appearance |
White or off white crystalline powder |
white crystalline powder |
Identification
|
Infrared absorption <197K> |
Complies |
The retention time of the major peak of the Sample solution corresponds to that in the chromatogram of the standard solution |
Related Substance |
α-Epoxyabirater-one acetate ≤0.25%
β- Epoxyabirater-one acetate ≤0.25%
Abiraterone≤0.20%
Abiraterone ethyl ether≤0.20%
Abiraterone isopropyl ether≤0.20%
Unspecified impurity≤0.10%
Total impurity≤0.80%
|
Not detected
Not detected
0.11%
Not detected
Not detected
0.06%
0.19%
|
Water |
≤0.25% |
0.17% |
Residual solvent |
Methanol≤0.3%
Dichloromethane≤0.06%
|
Not detected
Not detected
|
Residue on ignition |
≤0.1% |
0.05% |
Heavy metal |
≤10ppm |
Complies |
Assay |
98.0%–102.0% |
99.8% |
Conclusion: The product conforms to the USP39 standard |
-FAQ-
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2007.
Q2:Which kind of payment terms do you accept?
For small order,you can pay by T/T, Western Union or Money Gram
Q3:Can you give me a discount price?
Surely, It depend on your qty
Q4:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero.
If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
We could also provide Abiraterone powder, should you have any questions or demand, pls feel free to contact us: sales@mellonpharm.com.
http://www.mellonpharm.com/